David Arquette Deputy Dewey Riley Neve Campbell Sidney Prescott Courteney Cox Gale Weathers Matthew Lillard Stu Macher Rose McGowan Tatum Riley Skeet Ulrich Billy Loomis Jamie Kennedy Randy Meeks W. Earl Brown Kenny Liev Schreiber Cotton Weary Joseph Whipp Sheriff Burke Drew Barrymore Casey Becker Roger L. Jackson Ghostface (voice) Kevin Patrick Walls Steve Orth Lawrence Hecht Mr. Prescott Frances Lee McCain Mrs. Riley Ryan Kennedy Expelled Teen #2 Lisa Canning Reporter with Mask Henry Winkler Principal Arthur Himbry (uncredited) Linda Blair Obnoxious Reporter (uncredited) Cabran E. Chamberlain Boom Operator (uncredited) Wes Craven Fred the Janitor (uncredited) Lynn McRee Maureen Roberts Prescott (uncredited)