Timothée Chalamet Paul Atreides Rebecca Ferguson Lady Jessica Atreides Oscar Isaac Duke Leto Atreides Josh Brolin Gurney Halleck Stellan Skarsgård Baron Vladimir Harkonnen Dave Bautista Beast Rabban Harkonnen Sharon Duncan-Brewster Dr. Liet Kynes Stephen McKinley Henderson Thufir Hawat Zendaya Chani Chang Chen Dr. Wellington Yueh Charlotte Rampling Reverend Mother Gaius Helen Mohiam Jason Momoa Duncan Idaho Javier Bardem Stilgar David Dastmalchian Piter de Vries Babs Olusanmokun Jamis Golda Rosheuvel Shadout Mapes Roger Yuan Lieutenant Lanville Benjamin Clémentine Herald of the Change Souad Faress Bene Gesserit Sister Seun Shote Arrakeen Residency Gardener Neil Bell Sardaukar Bashar Oliver Ryan Hawat Specialist Stephen Collins Harkonnen Trooper Charlie Rawes Harkonnen Trooper Jean Gilpin Bene Gesserit Ancestor (voice)